Doctor’s Best Vitamin D3 5000 IU Softgels for Men & Women – Vitamin D Supplement for Immune System & Heart Health Support, 125 mcg per Serving, Vit D 3, Non GMO, Gluten Free, Soy Free – 360 Softgels

Vitamin d from dietary intake or sun exposure requires two activation steps in the body. The first activation occurs in the liver, while the second activation occurs in the kidneys, allowing for regulation of calcium metabolism. However, vitamin d receptors are present throughout the body, in tissue such as the skin, cartilage, heart, prostate, bones and intestines. Thus, the second activation step also takes place in local tissues. Recent discoveries have highlighted the important modulatory effects of vitamin d on various cells of the immune system.vitamin d enhances and regulates immune function. It is known that various cells of the immune system, such as t lymphocytes and antigen presenting cells, express the vitamin d receptor on their surface when activated. Recently, it has been found that treatment of these immune cells with vitamin d influences their expression of cytokines, which are chemical messengers of the immune system. The immune modulating effects of vitamin d extend to monocytes and dendritic cells of the immune system as well. Dendritic cells are important antigen-processing cells of the immune system that function to initiate the immune response. Vitamin d may prevent overactivity of the immune response and keep the immune system in a normal healthy state of vigilance.vitamin d supports optimal cardiovascular function. Research has uncovered the role vitamin d plays in supporting cardiac function. Heart myocytes (cells) express the vitamin d receptor, as do smooth muscle cells of blood vessels. The benefits of vitamin d on the heart are potentially far-reaching. Studies on mice heart cells have shown that vitamin d administration impacts their growth and proliferation. In these cells, vitamin d inhibited the release of a protein that could be detrimental to the function of these cells, displaying cardioprotective properties. It has also been shown that vitamin d has a modulatory effect on heart rhythm.
Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 2.19 x 2.19 x 4.25 inches; 3.84 ounces
Item model number ‏ : ‎ DRB-00250
Date First Available ‏ : ‎ May 18, 2011
Manufacturer ‏ : ‎ Doctor’s Best, Inc
ASIN ‏ : ‎ B0050MYHBQ
Best Sellers Rank: #6,220 in Health & Household (See Top 100 in Health & Household) #42 in Vitamin D Supplements #717 in Sales & Deals
Customer Reviews: 4.8 4.8 out of 5 stars (26,384) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
VITAMIN D3 SUPPLEMENT: This high-potency vitamin D formula provides the essential sunshine nutrient, supporting overall health when dietary intake or sun exposure is limited
IMMUNE HEALTH SUPPORT: Vitamin D3 helps maintain a healthy immune system, supporting the body’s natural defenses and overall wellness for adults
BONE STRENGTH & HEART FUNCTION: This vitamin D3 supplement helps calcium absorption for strong bones and supports healthy heart function and cardiovascular wellness
5000 IU PER SERVING: Each serving delivers 125 mcg (5000 IU) of vitamin D3 in non-GMO, gluten-free, and soy-free softgels, providing natural nutrient support
DOCTOR’S BEST: Good nutrition starts with sound science. For over 35 years, we have been dedicated to providing only thoroughly researched, rigorously tested, and clinically-approved supplements